Best Joint Supplement 2024

What are the best joint supplements, and should you take them?

Updated 4th January 2024
Fact Checked By Dr Mark Watson

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What Do We Look For In The Best ​Joint Health Supplements?

When recommending joint supplements we make sure that we've tried and tested them ourselves, but we also study the ingredients carefully against all the studies that are currently available. We listen to customers, run surveys and do our very best to make sure all our information is as accurate as it can be. In short we judge the products on our best joint supplements list on the following criteria:

Quality of ingredients
How well they work for joint pain
Long Term Joint Health Benefits
Swelling Reduction
Any Specialized Effects
Customer Satisfaction

This means that you can be sure you're getting a quality product with proven health benefits. We will outline the pros and cons of each supplement and we also compare the supplements against what they claim to do, so you just get legitimate information, not marketing hype. Think more omega oil and less snake oil.

Joint supplements can help reduce joint pain, and promote long term joint health, but they're unlikely to completely remove the aches and pains of getting older. But, they definitely can help. We won't knock points off for overhyped marketing, although it does typically reduce customer satisfaction. We also try to avoid proprietary blends as we cannot be sure if the doses of each ingredient are high enough to be effective.


- Best Overall 

Physio Flex Pro - Best Joint Supplement For Inflammation

Relief Factor
- Most Popular Joint Supplements 

Nordic Oils Omega
- Best Omega Oil Supplement For Joints 

Joint Buddy - Best Budget Joint Supplement

Best Joint Supplement FAQ

The most common questions we found when looking for the best joint supplements.

What are the best joint supplements for arthritis pain relief?

When it comes to treating arthritis pain and improving joint function omega 3 fatty acids [1], turmeric [2] and resveratrol [3] are typically deemed to be the most effective ingredients for natural rheumatoid arthritis pain. As such we'd typically recommend supplements for arthritis that contain all three. 

Are joint supplements FDA approved?

Natural joint supplements do not require individual FDA approval, however, they should still be produced in line with the USA's manufacturing guidelines. Joint health supplements that are not in line with guidelines or contain unlisted ingredients can however be removed from the market for breach of guidelines. 

Do Joint Supplements Work?

The short answer is yes, the longer answer is not all of them do, and they're often overhyped in terms of marketing. Supplements for joint pain can work, and they will often reduce symptoms of arthritis, but they're unlikely to completely cure the condition as some companies claim. However many supplements are horribly under dosed, meaning they are entirely ineffective. 

Can Calcium Supplements Ease Joint Pain?

Despite common belief calcium is not effective for treating joint pain. [4] It has been commonly promoted by supplements over the years, but recent studies have shown that it has no efficacy in reducing pain. For long term joint health it is beneficial, however if the problem is already there, it won't do anything to reduce pain.

Are Joint Supplements Safe?

For the most part yes, there are potentially some interactions with medications, for example omega 3 can have a mild blood thinning effect, which does not mix well with some medications or conditions [5]. Of course there are always the risks of allergens. But, for most people the most likely issue with joint pain supplements are likely to be mild nausea which can usually be resolved by taking the pills with food. 

FlexAgain - Best Joint Supplement Overall

Ever since FlexAgains made it’s way over from England to the our side for the pond, it's been impossible to beat as the best joint supplement in the USA. In fact, nothing else is even close. The only reason we’d recommend any of the other supplements on our list is for if some reason you can’t take on of the ingredients in FlexAgain or if you're looking for a lower budget option.

It boasts pretty much every ingredient that’s in everything else on our best list, in effective dosages and is priced cheaper than some of the competitors, with completely transparent labelling we don't know of any natural supplements that are better options to relieve pain or joint discomfort. 

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FlexAgain Ingredients

This is quite a long list, but FlexAgain contains 1100mg of omega 3 (from algae), 500mg curcumin extract, 250mg of Eurovita Extract 77 (shown to be as effective as 3000mg ginger) 400mg glucosamine HCL, 250mg chondroitin, 100mg bromelain, 100mg Boswellic acid, 100mg resveratrol as well as Vit D and Vit K2. All of these dosages are in the effective range and every single one is listed on the arthritis foundation's researched supplements list. Many of us already know about why omega oils are effective, and vitamin d and k2 deficiencies can cause joint pain. The interesting include resveratrol, which has been shown to improve overall joint health, and brain health. It works in a similar way to the body as omega oils, but adds additional benefits. Next we have glucosamine HCL is the higher concentration form of glucosamine sulphate, which is a collagen in a lot of the other top supplements, and even prescribed in some countries. 500mg of Curcumin has been shown to reduce pain in chronic arthritis cases and improve osteoarthritis symptoms as well as recovering from injury. Then there's the Ginger and Galangal extract which has been shown to increase joint mobility, reduce pain relief reliance and reduce joint swelling.

Who Is FlexAgain For?

  • Pretty much anyone looking to improve joint pain management
  • People who aren't allergic to any of the ingredients

FlexAgain Rating

The only negatives we have to say about FlexAgain is that, it's glucosamine is not stated to be from a vegan source, so it may not be suitable even if their omega source is and that you do have to take 2 pills twice a day. The last issue is that they list MSM, which they underdose, it's not really suitable for combined supplements as it requires 3 full joint pills to be effective. Everything else is ideally dosed, and it pretty much covers every single base that we'd expect from a joint supplement. To be quite honest, this is almost exactly what we'd have put into a supplement ourselves.

Criteria Rating
Ingredients 10/10
Pain Relief 10/10
Joint Health 10/10
Swelling 10/10
Value 9/10
Recommended 9.5/10
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Nordic Naturals Omega-3 - Best Omega Oil

There are quite a few different omega oil supplements on the market, and there's a whole host of ones that could've made this slot. The reality is that for the most part they're very similar, and what it comes down to is, do they have a quality capsule, what's the price point and are they high enough dosed. Whilst the dosage could be higher, it's easy enough to take an extra pill if that better suits your size and needs.

They're made from fish oil, which means they're less easily absorbed by the body than krill oil supplements, but they have higher volumes of DHA and EPA's the fatty acids that are beneficial for maintaining healthy joints. It's a lot cheaper than Omega XL, the markets most well known Omega joint supplement.

And seeing as a lot of people complain about the taste of fish oil supplements, the lemon flavor is a nice touch, which would be a winner with a lot of people. In short omega oils shouldn't be expensive as a stand alone, so good value, means good sense.

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What Ingredients Are In The Best Joint Supplements

Vit D - Vitamin D deficiency, which almost half of US adults have, can exacerbate joint pain, as such vitamin D supplements may help alleviate chronic pain and joint inflammation. [9]

Vit K2 - Vitamin K is important for healthy functioning of proteins in cartilage and bone, vitamin K2 is the more bioavailable (easily absorbed) version of vitamin K.

Omega 3 has long been known to be essential for joint health, most studies that have tested it for this purpose have focused on EPA (Eicosapentaenoic Acid) and DHA (Docosahexaenoic Acid) the two most well known omega 3 fatty acids. Doses over 1000mg are required for it to be effective based on the majority of studies.

Turmeric extract often referred to as curcumin has been shown to reduce inflammation and offer pain relief to people struggling with chronic joint pain. The arthritis foundation says curcumin blocks inflammatory cytokines and enzymes, which is the same way some none over the counter medications operate. Dosages that have been trialled effectively were 500mg capsules of the extract with 1000mg daily looking to be ideal. Studies have shown it to be effective at treating symptoms and may help delay breakdown.

Methylsulfonylmethane (MSM) has been shown to be effective at treating arthritis pain, however, the trials that have taken place so far were limited to studying knee pain.

Ginger extract has been shown to moderately reduce RA pain, the most effective trials used Eurovita Extract 77 a specific ginger extract at 255mg, but ginger itself has also shown to be effective.

Glucosamine and Chondroitin are often prescribed for joint pain in many European countries, considering the amount of evidence backing their use we're not sure why the US has not followed suit, fortunately they're readily available over the counter. Supplementation with Glucosamine sulfate did help those with moderate to mild pain, however, it did not do much for those suffering with more severe joint discomfort.

Bromelain - Initial studies are very positive about bromelain being used to treat joint pain, it's still relatively new, so more studies are required. But, it's a common inclusion in the best supplements for arthritis.

Boswellic acid appears to be an effective anti inflammatory agent, this enables it to improve joint function, and reduce muscle pain. Whilst it requires further trials it currently shows signs of being a positive over the counter treatment.

Does The Type Of Joint Pain Matter For Supplements?

The type of joint issues does matter when it comes to how to treat it, particularly when it comes to arthritis symptoms. For example, some supplements that work to treat osteoarthritis require doses 3-5 times higher to be effective at dealing with RA issues [6]. And some ingredients like bromelain which have numerous studies showing positive anti-inflammatory effects for OA didn’t show much improvement for RA. 

Ginger and Curcumin were however consistent across both conditions for example. But ginger required a minimum dose of 4 grams to have an impact for RA, but only 1 gram to make a difference to people suffering from OA. Most of the ingredients with anti inflammation effects are good across the board for joint conditions, but certain ingredients are more beneficial than others. 

Curcumin had added benefits for RA and seems to prevent further breakdown in animal models, making it potentially more important than some other ingredients for people with the condition as it may slow progression. [10] 

Fact Checked By Dr Mark Watson MD

Dr Mark Watson is the founder of Center TRT, having graduated from stamford more than 20 years ago, he is an expert in the field of supplemental health, focusing on long term benefits of complimenary treatment. View Bio


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